Faculty Profile
- Bio
- Publication
- Conference Papers
- Funded Projects
Dr. Muhammad Akram; Researcher; Principal Investigator; Scientist; Pharmacologist
Research Profiles
Research Area
| Research Areas |
|---|
| Anti-inflammatory activities of natural and synthetic compounds in In Vitro/In Vivo systems. |
| TPA/oxazolone induced inflammatory skin models |
| Inflammatory signaling |
| Underlying molecular mechanisms of anti-inflammatory drugs |
| Designing animal models of hepatotoxicity |
| Designing animal models of arthritis |
| Identifying hepatoprotective activity of natural compounds |
| Skills |
|---|
| Biochemical and immunoassays: Nitric oxide assay, ABTS assay, DPPH assay, Lipid peroxidation assay, MTT cell cytotoxicity assay, Prostaglandins assay, Interleukins & TNF-α determination |
| RNA extraction from cells and tissues |
| cDNA synthesis |
| Cell culture: RAW 264.7 macrophage & Human keratinocytes cell culture |
| Western blot analysis |
| Real Time PCR analysis |
| Animal handling, drug dosing by oral & parenteral routes |
| Collection of tissue biopsies & blood samples from rats & mice |
| In vivo models of topical and systemic inflammation |
| In vivo models of nociception |
| In vivo models of Ischemic stroke (MCAO model) |
| Histological analysis of the animal tissues |
| In vitro anti-oxidant activity |
| Cell culture |
| No. | Journal Publications |
|---|---|
| 1. |
Tannic acid inhibits lipopolysaccharide-induced cognitive impairment in adult mice by targeting multiple pathological featuresAuthors: Ullah, Rahim, Gowhar Ali, Abdul Baseer, Sumaira Irum Khan, Muhammad Akram, Saifullah Khan, Nisar Ahmad,
|
| 2. |
Assessment of Patient?s Response about Adverse Drug Reactions Receiving AC (Adriamycin, Cyclophosphamide) Therapy: A Survey ResearchAuthors: Jamali, Jameela, Abdullah Dayo, Naheed Memon, Muhammad Akram Khatri, Shaib Muhammad, Yasmeen Qureshi, and Tooba Khan,
|
| 3. |
Assessment of Drug Utilization of Antimicrobials in Different Infectious Diseases at Various Clinics of Sanghar, PakistanAuthors: Laghari, Saif-ul-Rehman, Muhammad Aslam, Muhammad Akram Khatri, Abdullah Dayo, Muhammad Ali Ghoto, Mudassar Iqbal Arain, Rabia Parveen, and Ahsan Ali Memon,
|
| 4. |
Simple and Fast Determination of Cefpodoxime and its Schiff\'s Base Derivative Using Colorimeteric TechniqueAuthors: Maheshwari, Madan L., Geeta Kumari, Akram Khatri, Narendar Kumar, Hosh M. Lashari, Abdul H. Memon, Ubed R. Mughal, and Saeed A. Lakho,
|
| 5. |
A New Iridoid Compound Isolated from Aerial Parts of Actinidia polygama and Determination of its Antioxidant ActivityAuthors: Ahmed Shah SYED, Chul Young KIM, Muhammad AKRAM & Geeta KUMARI,
|
| 6. |
Attenuation of Spatial Memory in 5xFAD Mice by Halting Cholinesterases, Oxidative Stress and Neuroinflammation Using a Cyclopentanone DerivativeAuthors: Ullah, Rahim, Gowhar Ali, Nisar Ahmad, Muhammad Akram, Geeta Kumari, Muhammad Usman Amin, and Muhammad Naveed Umar,
|
| 7. |
Autophagy-mediated occludin degradation contributes to blood–brain barrier disruption during ischemia in bEnd. 3 brain endothelial cells and rat ischemic stroke modelsAuthors: Kim, Kyeong-A., Donghyun Kim, Jeong-Hyeon Kim, Young-Jun Shin, Eun-Sun Kim, Muhammad Akram, Eun-Hye Kim, Arshad Majid, Seung-Hoon Baek, and Ok-Nam Bae,
|
| 8. |
Isocassiaoccidentalin B, a new C‐glycosyl flavone containing a 3‐keto sugar, and other constituents from Cassia nomameAuthors: Ahmed Shah Syed, Muhammad Akram, Ok‐Nam Bae, Chul Young Kim,
|
| 9. |
Frequency and duration of adverse drug reactions in pakistan receiving anticancer Combination Therapy at Cancer Hospital Jamshoro, PakistanAuthors: ameela JAMALI, Abdullah DAYO, Naheed MEMON, Muhammad A. GHOTO, Muhammad A. KHATRI, Yasmeen QURESHI, Salman A. RAJPUT & Tooba KHAN,
|
| 10. |
A Rare Threono-1,4-Lactone Containing Flavone Glycoside from Cassia nomameAuthors: Ahmed Shah Syed, Muhammad Akram, Ok-Nam Bae, Chul Young Kim,
|
| 11. |
Enhanced anti-rheumatic activity of methotrexate-entrapped ultradeformable liposomal gel in adjuvant-induced arthritis rat modelAuthors: Zeb, Alam, Omer Salman Qureshi, Chan-Hee Yu, Muhammad Akram, Hyung-Seo Kim, Myung-Sic Kim, Jong-Ho Kang,
|
| 12. |
Enhanced acute anti-inflammatory effects of CORM-2-loaded nanoparticles via sustained carbon monoxide deliveryAuthors: Omer Salman Qureshi, Alam Zeb, Muhammad Akram, Myung-Sic Kim, Jong-Ho Kang, Hoo-Seong Kim, Arshad Majid, Inbo Han, Sun-Young Chang, Ok-Nam Bae, Jin-Ki Kim,
|
| 13. |
A newly synthesized macakurzin C-derivative attenuates acute and chronic skin inflammation: the Nrf2/heme oxygenase signaling as a potential targetAuthors: Akram, Muhammad, Iljin Shin, Kyeong-A. Kim, Dabi Noh, Seung-Hoon Baek, Sun-Young Chang, Hyoungsu Kim, and Ok-Nam Bae.,
|
| 14. |
Selective inhibition of JAK2/STAT1 signaling and iNOS expression mediates the anti-inflammatory effects of coniferyl aldehydeAuthors: Muhammad Akram, Kyeong-A Kim, Eun-Sun Kim, Young-Jun Shin, Dabi Noh, Eunji Kim, Jeong-Hyeon Kim, Arshad Majid, Sun-Young Chang, Jin-Ki Kim, Ok-Nam Bae,
|
| 15. |
Potent anti-inflammatory and analgesic actions of the chloroform extract of Dendropanax morbifera mediated by the Nrf2/HO-1 pathwayAuthors: Akram, Muhammad, Kyeong-A. Kim, Eun-Sun Kim, Ahmed Shah Syed, Chul Young Kim, Jong Soo Lee, and Ok-Nam Bae.,
|
| 16. |
Heme oxygenase 1-mediated novel anti-inflammatory activities of Salvia plebeia and its active componentsAuthors: Akram, Muhammad, Ahmed Shah Syed, Kyeong-A. Kim, Jong Soo Lee, Sun-Young Chang, Chul Young Kim, and Ok-Nam Bae,
|
| 17. |
Protective activity of Dendropanax morbifera against cisplatin-induced acute kidney injuryAuthors: Eun-Sun Kim, Jong Soo Lee, Muhammad Akram, Kyeong-A Kim, Young-Jun Shin, Jong-Hyun Yu, Ok-Nam Bae,
|
| 18. |
Modulation of mitochondrial function and autophagy mediates carnosine neuroprotection against ischemic brain damageAuthors: Seung-Hoon Baek, Ah Reum Noh, Kyeong-A. Kim, Muhammad Akram, Young-Jun Shin, Eun-Sun Kim, Seong Woon Yu, Arshad Majid, and Ok-Nam Bae,
|
| 19. |
High glucose condition induces autophagy in endothelial progenitor cells contributing to angiogenic impairmentAuthors: Kyeong-A Kim, Young-Jun Shin, Muhammad Akram, Eun-Sun Kim, Ko-Woon Choi, Hyewon Suh, Chul-Hoon Lee, Ok-Nam Bae,
|
| 20. |
IMPACT OF IMPROPER PATIENT COUNSELLING FACTOR IN DRUG MISUSE / ABUSE: A CASE STUDY OF HYDERABAD CITY, PAKISTANAuthors: Muhammad Ali Ghoto, Abdullah Dayo, Naeem Tariq Narejo ,Mohsin Ali Baloch, Muhammad Akram, Imran Surehyani, Abbas Ali.,
|
| 21. |
Identification of errors in antibiotics prescriptions and prescription writing trends in areas of Hyderabad Sindh, PakistanAuthors: Ghoto, Muhammad Ali, Abdullah Dayo, Muhammad Akram, Imran Surehyani, and Abbas Ali,
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| No. | Conference Publications |
|---|---|
| No records found! | |
| NO. | Project Title | Role | National/International | Start Date | End Date |
|---|---|---|---|---|---|
| No records found! | |||||
| NO. | Supervisior/Co-Supervisor | Student Name | Research Title | Is-Complete | Program | Topic Register Date |
|---|---|---|---|---|---|---|
| 1. | Supervisor | Fatima, Shaikh | Assessment Of Anti-oxidant And Hepatoprotective Potential Of Euphorbia Milii Against Carbon Tetra Chloride Induced Hepatic Damage In Experimental Rats | Yes | MS/M.Phil | June, 05 2017 |
| NO. | Supervisior/Co-Supervisor | Student Name | Project Title | Is-Complete | Department | Year |
|---|---|---|---|---|---|---|
| No records found! | ||||||